INO-1001 mesylate
Based on 2 publication(s) in Google Scholar
INO-1001 mesylate is a potent and selective poly (ADP-ribose) polymerase (PARP) inhibitor. INO-1001 mesylate is a potent enhancer of radiation sensitivity and enhances radiation-induced cell killing by interfering with DNA repair mechanisms, resulting in necrotic cell death. INO-1001 mesylate has anti-tumor effects.
For research use only. We do not sell to patients.
- CAS No.: 501364-91-6
- Formula: C24H29N3O7S2
- Molecular Weight:535.63
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Publications Citing Use of MedChemExpress (MCE) INO-1001 mesylate
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Biological Activity
Chemical Information
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CAS No. 501364-91-6
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Molecular Weight 535.63
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Formula C24H29N3O7S2
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SMILES
O=S(O)(C)=O.O=C1NC2=C(C3=CC=CC=C31)CC4=C2C=CC(S(NCCCN5CCOCC5)(=O)=O)=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (2)
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Journal Impact Factor
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Most Recent
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J Virol
Porcine Reproductive and Respiratory Syndrome Virus Activates Lipophagy To Facilitate Viral Replication through Downregulation of NDRG1 Expression. [Abstract]2019 Aug 13;93(17):e00526-19. PMID: 31189711 -
Purity & Documentation
References
[1]. Brock WA, et al. Radiosensitization of human and rodent cell lines by INO-1001, a novel inhibitor of poly(ADP-ribose) polymerase. Cancer Lett. 2004 Mar 18;205(2):155-60. [Content Brief]
[2]. Mason KA, et al. INO-1001, a novel inhibitor of poly(ADP-ribose) polymerase, enhances tumor response to doxorubicin. Invest New Drugs. 2008 Feb;26(1):1-5. Epub 2007 Jul 13. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
INO-1001 mesylate Related Classifications
HY-15045A Related Classifications
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