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Cat. No.: HY-N14715

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Gypsetin

Gypsetin can inhibit acylcoenzyme A, cholesterol acyltransferase (ACAT) activity, inhibit rat liver microbody ACAT with an IC₅₀ of 18 μM, and its action is competitive with oleoyl-COA substrate, K_i value is 5.5 μM. Gypsetin also inhibits Oleic acid from forming cholesterol esters with an IC₅₀ of 0.65 μM.

For research use only. We do not sell to patients.

CAS No.: 155114-38-8
Formula: C₃₂H₃₆N₄O₄
Molecular Weight:540.65

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

Gypsetin Chemical Structure

CAS No.: 155114-38-8

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All Acyltransferase Isoforms :

Chemical Information

CAS No. 155114-38-8
Molecular Weight 540.65
Formula C₃₂H₃₆N₄O₄
SMILES

C=CC(C)([C@]12[C@](C3=CC=CC=C3N1)(C[C@]4([H])N2C([C@@]5([H])N([C@@]6([C@](C5)(C7=CC=CC=C7N6)O)C(C)(C)C=C)C4=O)=O)O)C
Structure Classification
- Others
Initial Source
- Microorganisms
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. B Nuber, et al. Gypsetin, a new inhibitor of acyl-CoA: cholesterol acyltransferase produced by Nannizzia gypsea var. incurvata IFO 9228. II. Structure determination. J Antibiot (Tokyo). 1994 Feb;47(2):168-72. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Gypsetin

All Acyltransferase Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Gypsetin Related Classifications

HY-N14715 Related Classifications