PF-4522654
PF-4522654 is a potent, selective and brain-permeable 5-HT2C receptor agonist with an EC50 of 16 nM and a Ki of 8 nM. PF-4522654 shows no measurable functional agonism at no 5-HT2A and 5-HT2B receptors. PF-4522654 can be used for the study of stress urinary incontinence (SUI).
For research use only. We do not sell to patients.
- CAS No.: 1065109-28-5
- Formula: C16H18F2N4
- Molecular Weight:304.34
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All 5-HT Receptor Isoforms
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Biological Activity
|
5-HT2A Receptor |
5-HT2B Receptor |
5-HT2C Receptor |
5-HT2C Receptor 16 nM (EC50) |
5-HT2C Receptor 8 nM (Ki) |
5-HT2B Receptor >10000 nM (EC50) |
Chemical Information
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CAS No. 1065109-28-5
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Molecular Weight 304.34
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Formula C16H18F2N4
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SMILES
FC(C1=NC(CCNCC2)=C2C(NC)=N1)(C3=CC=CC=C3)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PF-4522654 Related Classifications
HY-124947 Related Classifications
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