1. Immunology/Inflammation
    Protein Tyrosine Kinase/RTK
  2. PD-1/PD-L1
  3. Ivonescimab

Ivonescimab  (Synonyms: AK112)

Cat. No.: HY-P99675

Ivonescimab (AK112) is a PD-1/VEGF Bispecific Antibody. Ivonescimab can be used for cancer research.

For research use only. We do not sell to patients.

Ivonescimab Chemical Structure

Ivonescimab Chemical Structure

CAS No. : 2428381-53-5

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Ivonescimab (AK112) is a PD-1/VEGF Bispecific Antibody. Ivonescimab can be used for cancer research[1][2][3].

In Vitro

Ivonescimab binds to PD-1 and VEGFA with EC50s of 0.06 and 0.036 nM[2].
Ivonescimab can form soluble complexes with VEGF (by SEC-HPLC assay)[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.




Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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