Calf thymus DNA
Based on 7 publication(s) in Google Scholar
Calf thymus DNA (DNA from calf thymus) is high quality double-stranded template DNA isolated from the thymus of male and female calves. Calf thymus DNA can be used for the research of the interaction between DNA and agents.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 91080-16-9
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保管条件:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
MedChemExpress(MCE)の使用を引用している文献 Calf thymus DNA
More- Nat Commun. 2024 Dec 5;15(1):10599. [Abstract]
- J Med Chem. 2026 Jun 25;69(12):14492-14512. [Abstract]
- J Ethnopharmacol. 2025 Feb 11:341:119304. [Abstract]
- Pharm Res. 2026 May 27. [Abstract]
- J Transl Autoimmun. 2026 Jan 12:12:100349. [Abstract]
- chemRxiv. 2025 Dec 22.
- Biomed Pharmacother. 2024 Jun:175:116794. [Abstract]
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ELISA
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ELISA
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ELISA
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Bio/Physico-chemical Assay
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Bio/Physico-chemical Assay
DNA/RNA Synthesis アイソフォーム固有の製品をすべて表示
More
生物活性
Calf thymus DNA interacts with the antiviral drug Lamivudine that can be studied using emission, absorption, circular dichroism (CD), and viscosity techniques[2].
Note: To reduce DNA shearing, sonication or agitation should not be used. It's recommended to shake gently overnight at 0-4°C to completely dissolve the DNA.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 91080-16-9
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性状 Solid
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Color White to light yellow
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SMILES
[Calf thymus DNA]
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別名
DNA from calf thymus, Thymonucleic acid
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Structure Classification
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Initial Source
the thymus of male and female calves
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (7)
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Journal Impact Factor
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Most Recent
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Nat Commun
Aberrant METTL1-mediated tRNA m7G modification alters B-cell responses in systemic autoimmunity in humans and mice. [Abstract]2024 Dec 5;15(1):10599. PMID: 39638793 -
J Med Chem
Structure-Guided Discovery of Potent, Selective, and Orally Bioavailable Werner Syndrome RecQ Helicase Inhibitors for the Treatment of Microsatellite Instability-High Tumors. [Abstract]2026 Jun 25;69(12):14492-14512. PMID: 42234810 -
J Ethnopharmacol
Investigating the mechanism of Tongfeng Qingxiao Formula for improving gouty arthritis based on the neutrophil extracellular trapping network. [Abstract]2025 Feb 11:341:119304. PMID: 39736350 -
Pharm Res
Rational Design, Optimization and Bioinformatic Analysis of Anti-PD-L1 Peptide Conjugated Mocetinostat Prodrug Nanoparticles for Predictive Cancer Chemoimmunotherapeutic Efficacy. [Abstract]2026 May 27. PMID: 42204129 -
J Transl Autoimmun
Liraglutide prevents lupus-associated diffuse alveolar hemorrhage via inhibiting lymphocyte infiltration and promoting macrophage M2 polarization. [Abstract]2026 Jan 12:12:100349. PMID: 41626528 -
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Biomed Pharmacother
Ginsenoside Rb1 mitigates acute catecholamine surge-induced myocardial injuries in part by suppressing STING-mediated macrophage activation. [Abstract]2024 Jun:175:116794. PMID: 38776673
Calf thymus DNA purchased from MedChemExpress. Usage Cited in: Biomed Pharmacother. 2024 Jun:175:116794. [Abstract]
RAW264.7 cells were treated with either vehicle or Rb1 at 50, 100, 200 and 400 μM in the presence or absence of 2 μg/ml ctDNA (Calf thymus DNA) stimulation. The levels of TNFα, IL6 and CCL2 in the culture supernatants collected 3 h post ctDNA stimulation were analyzed by ELISA.
Calf thymus DNA purchased from MedChemExpress. Usage Cited in: Biomed Pharmacother. 2024 Jun:175:116794. [Abstract]
The supernatants were collected 6 h post ctDNA (Calf thymus DNA) stimulation and the production of TNFα, IL6, CCL2 and IFN-β was quantified by ELISA.
Calf thymus DNA purchased from MedChemExpress. Usage Cited in: Biomed Pharmacother. 2024 Jun:175:116794. [Abstract]
The supernatants collected 12 h post ctDNA (Calf thymus DNA) stimulation were analyzed by ELISA to quantify the level of TNFα, IL6, CCL2 and IFN-β.
Calf thymus DNA purchased from MedChemExpress. Usage Cited in: Biomed Pharmacother. 2024 Jun:175:116794. [Abstract]
Volcano plot of DEGs from the ctDNA (Calf thymus DNA) vs Ctrl. C. Line charts categorizing DEGs (ctDNA vs Ctrl) using Mfuzz clustering.
Calf thymus DNA purchased from MedChemExpress. Usage Cited in: Biomed Pharmacother. 2024 Jun:175:116794. [Abstract]
Enriched pathways revealed by GSEA (Rb1 vs ctDNA (Calf thymus DNA)). Ctrl, vehicle-treated RAW264.7 cells; ctDNA, vehicle-treated ctDNA-stimulated RAW264.7 cells; Rb1, Rb1-treated ctDNA-stimulated RAW264.7 cells; NES normalized enrichment score.
溶剤 & 溶解度
H2O : ≥ 1 mg/mL
* "≥" means soluble, but saturation unknown.
純度とドキュメンテーション
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データシート (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Liu F, et al. Cytotoxicity of Aconitum alkaloid and its interaction with calf thymus DNA by multi-spectroscopic techniques. Sci Rep. 2017 Nov 6;7(1):14509. [Content Brief]
[2]. Shahabadi N, et, al. Interaction of calf thymus DNA with the antiviral drug Lamivudine. DNA Cell Biol. 2012 Jan;31(1):122-7. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)