K-Ras G12C-IN-1
Based on 1 publication(s) in Google Scholar
K-Ras G12C-IN-1 is a novel and irreversible inhibitor of mutant K-ras G12C extracted from patent WO 2014152588 A1.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.19%
- CAS 番号: 1629265-17-3
- 分子式: C22H23Cl2N3O3
- 分子量:448.34
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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溶剤 & 溶解度
- 純度とドキュメンテーション
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MedChemExpress（MCE）の使用を引用している文献 K-Ras G12C-IN-1
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生物活性
化学情報
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CAS 番号 1629265-17-3
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性状 Solid
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分子量 448.34
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分子式 C22H23Cl2N3O3
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Color White to off-white
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SMILES
ClC(C=C(OC)C(NCC(N1CCN(C(C=C)=O)CC1)=O)=C2)=C2C3=CC=CC=C3Cl
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Publications (1)
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Journal Impact Factor
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Most Recent
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Cell Chem Biol
2026 Feb 11:S2451-9456(26)00027-9. PMID: 41679298
溶剤 & 溶解度
DMSO : ≥ 40 mg/mL (89.22 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (242 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2305 mL | 11.1523 mL | 22.3045 mL | 55.7613 mL |
| 5 mM | 0.4461 mL | 2.2305 mL | 4.4609 mL | 11.1523 mL | |
| 10 mM | 0.2230 mL | 1.1152 mL | 2.2305 mL | 5.5761 mL | |
| 15 mM | 0.1487 mL | 0.7435 mL | 1.4870 mL | 3.7174 mL | |
| 20 mM | 0.1115 mL | 0.5576 mL | 1.1152 mL | 2.7881 mL | |
| 25 mM | 0.0892 mL | 0.4461 mL | 0.8922 mL | 2.2305 mL | |
| 30 mM | 0.0743 mL | 0.3717 mL | 0.7435 mL | 1.8587 mL | |
| 40 mM | 0.0558 mL | 0.2788 mL | 0.5576 mL | 1.3940 mL | |
| 50 mM | 0.0446 mL | 0.2230 mL | 0.4461 mL | 1.1152 mL | |
| 60 mM | 0.0372 mL | 0.1859 mL | 0.3717 mL | 0.9294 mL | |
| 80 mM | 0.0279 mL | 0.1394 mL | 0.2788 mL | 0.6970 mL |
K-Ras G12C-IN-1 関連分類
HY-18604 関連分類
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