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製品番号: HY-120687

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A68930

1 Cited Publications

カスタマーレビュー

Based on 1 publication(s) in Google Scholar

A68930, as a dopamine D1 receptor agonist, can be used for the research of bronchiectasis.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 130465-45-1
分子式: C₁₆H₁₇NO₃
分子量:271.31

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

A68930 構造式

CAS 番号: 130465-45-1

容量

価格（税別）

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数量

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性
- 製品説明
- IC₅₀ & Target
- Cellular Effect
- 体外実験
化学情報
Publications (1)
純度とドキュメンテーション
参考文献
Calculators
Help & FAQs
関連分類
Bioz

生物活性

製品説明

A68930, as a dopamine D1 receptor agonist, can be used for the research of bronchiectasis^[1].

IC₅₀ & Target

D₁ Receptor

Dopamine Receptor アイソフォーム固有の製品をすべて表示 :

Cellular Effect

Cell Line	Type	Value	Description	References
Pituitary gland cell	EC₅₀	10200 nM Compound: 22	Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland	[PMID: 1652023]

体外実験

A68930 (1 μM; 5-60 minutes; 16HBE14o- or NCI-H292 cells) significantly increases phosphorylation of cAMP response element binding (CREB) protein^[1].
A68930 (1 μM; 48 hours; NCI-H292 cells) induces MUC5AC mRNA expression and increases the mRNA data of MUC5AC and MUC5AC protein expression^[1].
A68930 (1 μM; 20 minutes; NCI-H292 cells) significantly increases intracellular cAMP levels^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Western Blot Analysis^[1]

Cell Line:

16HBE14o- or NCI-H292 cells
Concentration:

1 μM
Incubation Time:

5~60 minutes
Result:

Significantly increased phosphorylation of CREB.

RT-PCR^[1]

Cell Line:

NCI-H292 cells
Concentration:

1 μM
Incubation Time:

48 hours
Result:

Induced MUC5AC mRNA expression.

Immunofluorescence^[1]

Cell Line:

NCI-H292 cells
Concentration:

1 μM
Incubation Time:

48 hours
Result:

The mRNA data of MUC5AC, MUC5AC protein expression were increased.

化学情報

CAS 番号 130465-45-1
分子量 271.31
分子式 C₁₆H₁₇NO₃
SMILES

OC1=C2C[C@H](O[C@H](C2=CC=C1O)CN)C3=CC=CC=C3
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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bioRxiv

Host GPCR-cAMP signaling balances Gαs and Gαi activity to control intracellular Brucella infection. [Abstract]

2026 Jan 6:2026.01.06.697936. PMID: 41542404

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (272 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Matsuyama N, et al. The dopamine D1 receptor is expressed and induces CREB phosphorylation and MUC5AC expression in human airway epithelium. Respir Res. 2018;19(1):53. Published 2018 Apr 2. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

A68930

1 Cited Publications

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生物活性
- 製品説明
- IC₅₀ & Target
- 体外実験
化学情報
Publications (1)
純度とドキュメンテーション
参考文献

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A68930

MedChemExpress（MCE）の使用を引用している文献 A68930

Dopamine Receptor アイソフォーム固有の製品をすべて表示

生物活性

化学情報

Publications (1)

純度とドキュメンテーション

参考文献

Calculators

Help & FAQs

A68930 関連分類

HY-120687 関連分類