AA 344
AA 344 is an orally active antiallergic agent. AA 344 inhibits the IgE, IgGa, Concanavalin A (HY-P2149), Dextran -mediated release of histamine. AA 344 shows inhibitory effects on the homologous passive cutaneous anaphylaxis and the passive systemic anaphylaxis in guinea pigs. AA 344 selectively suppresses the type I allergic reaction.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 50743-49-2
- 分子式: C12H10N4O2
- 分子量:242.23
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
Histamine Receptor アイソフォーム固有の製品をすべて表示
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生物活性
化学情報
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CAS 番号 50743-49-2
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分子量 242.23
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分子式 C12H10N4O2
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SMILES
O=C1C(C2=NN=NN2)=COC3=CC=C(CC)C=C13
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Saijo T, et al. Inhibitory action of 6-ethyl-3-(1H-tetrazol-5-YL)chromone (AA-344) on IgE, IgGa- or chemical agent-induced histamine release from isolated rat mast cells. Jpn J Pharmacol. 1979 Aug;29(4):531-40. [Content Brief]
[2]. Kuriki H, et al. Effect of 6-ethyl-3-(1H-tetrazol-5-yl)chromone (AA-344) on the immediate and delayed hypersensitivity reactions. Jpn J Pharmacol. 1979 Oct;29(5):733-44. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)