Analgesic agent-4
Analgesic agent-4 is an adenosine A3AR ligand with analgesic/antinociceptive activity. Analgesic agent-4 inhibits writhing responses in mice and exhibits dose-dependent activity in the acetic acid (HY-Y0319)-induced mouse writhing model. Analgesic agent-4 can be used in the research of pain-related diseases.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1179703-17-3
- 分子式: C11H8ClN3O2
- 分子量:249.65
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
Analgesic agent‑4 (Compound 37) can bind to the human adenosine A3 receptor, and this binding relies on conserved and enhanced hydrophobic interactions[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Mice treated Acetic acid (HY-Y0319)[1]
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Dosage:3-300 mg/kg
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Administration:s.c.; single dose
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Result:Produced a 47% writhing inhibition rate at 100 mg/kg.
Inhibited writhing in a dose-dependent manner within the range of 30-300 mg/kg.
化学情報
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CAS 番号 1179703-17-3
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分子量 249.65
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分子式 C11H8ClN3O2
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SMILES
OC(C=C1)=CC=C1NC(C2=CC=C(Cl)N=N2)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Analgesic agent-4 関連分類
HY-182782 関連分類
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