Andrimid
Andrimid is a peptide Antibiotic and acetyl-CoA carboxylase inhibitor. Andrimid is produced by symbiotic bacteria of the genus *Enterobacter* residing in the brown planthopper Nilaparvata lugens. Andrimid exhibits strong specific activity against Xanthomonas campestris pv. oryzae. Andrimid shows no or only weak activity against Gram-positive and Gram-negative bacteria, including most plant pathogenic bacteria. Andrimid can be used in studies related to bacterial infections and rice bacterial blight.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 108868-95-7
- 分子式: C27H33N3O5
- 分子量:479.57
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
Antibiotic アイソフォーム固有の製品をすべて表示
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生物活性
Andrimid (0.1 μg/mL) potently inhibits Xanthomonas campestris pv. oryzae strain NIAES 1225 with an MIC of 0.1 μg/mL and shows strong, specific activity against all tested Southeast Asian and Japanese X. campestris pv. oryzae strains, with significantly reduced activity against other bacterial pathovars and pathogens[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 108868-95-7
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分子量 479.57
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分子式 C27H33N3O5
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SMILES
C/C=C/C=C/C=C/C(N[C@H](C1=CC=CC=C1)CC(N[C@@H](C(C)C)C([C@H]2[C@@H](C(NC2=O)=O)C)=O)=O)=O
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Structure Classification
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Initial Source
Erwinia persicina BST187
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Matilla MA, et al. Biosynthesis of the acetyl-CoA carboxylase-inhibiting antibiotic, andrimid in Serratia is regulated by Hfq and the LysR-type transcriptional regulator, AdmX. Environ Microbiol. 2016;18(11):3635-3650. [Content Brief]
[3]. Cheng T, et al. Improved production of andrimid in Erwinia persicina BST187 strain by fermentation optimization. BMC Microbiol. 2023;23(1):268. Published 2023 Sep 25. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
- Andrimid
- 108868-95-7
- Bacterial
- Antibiotic
- Acetyl-CoA Carboxylase
- Enterobacter sp.
- Dickeya solani
- Bacillus subtilis
- Xanthomonas campestris pv. campestris
- Xanthomonas campestris pv. oryzae
- Serratia plymuthica A153
- Serratia marcescens MSU97
- acetyl-CoA carboxylase
- Nilaparvata lugens
- fatty acid biosynthesis
- Inhibitor
- inhibitor
- inhibit