Anthraquinone
Based on 3 publication(s) in Google Scholar
Anthraquinone is used as a precursor for dye formation and agrochemicals, existing in different organisms, such as bacteria, fungi, plants, and some animals. Anthraquinone has biological activities: anticancer, antiinflammatory, diuretic, antiarthritic, antifungal, antibacterial, antimalarial and antioxidant. Anthraquinone also plays an important role in the primary metabolism of plants by acting on the electron transport chain through the inhibition of energy transfer in the photosynthetic process. Anthraquinone can intercalates into DNA and inhibits the topoisomerase II (topo II) enzyme, resulting in cell death via Apoptosis.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.80%
- CAS 番号: 84-65-1
- 分子式: C14H8O2
- 分子量:208.22
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
MedChemExpress(MCE)の使用を引用している文献 Anthraquinone
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生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A2780 | IC50 |
0.58 μM
Compound: 12
|
Antiproliferative activity against human A2780 cells after 2 days by alamar-blue assay
Antiproliferative activity against human A2780 cells after 2 days by alamar-blue assay
|
[PMID: 19028102] |
| AGS | IC50 |
>100 μM
Compound: 1B
|
Cytotoxicity against human AGS cells assessed as cell viability after 72 hrs by MTT assay
Cytotoxicity against human AGS cells assessed as cell viability after 72 hrs by MTT assay
|
[PMID: 23454511] |
| HeLa | IC50 |
>50 μM
Compound: 12
|
Inhibition of histidine-tagged mouse MKP1 catalytic domain expressed in human Hela cells
Inhibition of histidine-tagged mouse MKP1 catalytic domain expressed in human Hela cells
|
[PMID: 19028102] |
| HL-60 | IC50 |
>100 μM
Compound: 1B
|
Cytotoxicity against human HL60 cells assessed as cell viability after 72 hrs by MTT assay
Cytotoxicity against human HL60 cells assessed as cell viability after 72 hrs by MTT assay
|
[PMID: 23454511] |
| J82 | IC50 |
>100 μM
Compound: 1B
|
Cytotoxicity against human J82 cells assessed as cell viability after 72 hrs by MTT assay
Cytotoxicity against human J82 cells assessed as cell viability after 72 hrs by MTT assay
|
[PMID: 23454511] |
| MRC5 | IC50 |
>100 μM
Compound: 1B
|
Cytotoxicity against human MRC5 cells assessed as cell viability after 72 hrs by MTT assay
Cytotoxicity against human MRC5 cells assessed as cell viability after 72 hrs by MTT assay
|
[PMID: 23454511] |
| SK-MES-1 | IC50 |
>100 μM
Compound: 1B
|
Cytotoxicity against human SKMES1 cells assessed as cell viability after 72 hrs by MTT assay
Cytotoxicity against human SKMES1 cells assessed as cell viability after 72 hrs by MTT assay
|
[PMID: 23454511] |
Anthraquinone (0.2 mg/mL, 3 min) shows a strong antioxidant activity in vitro[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 84-65-1
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性状 Solid
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分子量 208.22
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分子式 C14H8O2
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Color Light yellow to yellow
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SMILES
O=C1C2=C(C=CC=C2)C(C3=CC=CC=C13)=O
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別名
Anthraquinone
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (3)
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Journal Impact Factor
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Most Recent
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Vet Microbiol
The Chinese medicine monomer Schisandrin C inhibits PRRSV infection by regulating the OGT-PI3K/AKT/mTOR signaling pathway. [Abstract]2026 May:316:110992. PMID: 41865607 -
Cancer Manag Res
Dihydrocapsaicin Secreted by RYK Silenced Bone Marrow-Derived Mesenchymal Stem Cells Triggers Apoptosis of Gastric Cancer Cells. [Abstract]2026 Mar 21:18:579598. PMID: 41890221 -
溶剤 & 溶解度
DMSO : 2 mg/mL (9.61 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (277 KB)
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SDS (557 KB)
- English - EN (557 KB)
- Français - FR (557 KB)
- Deutsch - DE (557 KB)
- Norwegian - NO (557 KB)
- Español - ES (557 KB)
- Swedish - SV (557 KB)
- Italian - IT (557 KB)
- Korean - KR (557 KB)
- Portuguese - PT (557 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.8026 mL | 24.0131 mL | 48.0261 mL | 120.0653 mL |
| 5 mM | 0.9605 mL | 4.8026 mL | 9.6052 mL | 24.0131 mL |