Anticancer agent 121
Anticancer agent 121, an inhibitor of human lactate dehydrogenase A enzyme (hLDHA), has good anticancer activities and can be used for anticancer research.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2924532-47-6
- 分子式: C19H18N2O3S
- 分子量:354.42
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
Anticancer agent 121 (Compound 8j) (0-100 μM; 72 hours) has selective inhibition in HeLa and SiHa cervical cancer cell lines and has not noticeable toxicity in human embryonic kidney cell line HEK293 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:HEK293, HepG2, HeLa and SiHa
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Concentration:0-100 μM
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Incubation Time:72 hours
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Result:Inhibited cell growth with IC50s of 7.9 μΜ, 6.75 μΜ and 2.32 μΜ for HepG2, HeLa and SiHa cell lines.
Had not noticeable toxicity in HEK293.
化学情報
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CAS 番号 2924532-47-6
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分子量 354.42
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分子式 C19H18N2O3S
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SMILES
O=C(OC)C/N=C1SC=C(C2=CC=CC=C2)N/1C3=CC=C(OC)C=C3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)