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製品番号: HY-127039

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Antipain

Antipain is a protease inhibitor isolated from Actinomycetes. Antipain inhibits N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced transformation and increases chromosomal aberrations. Antipain restricts uterine DNA synthesis and function in mice.

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CAS 番号: 37691-11-5
分子式: C₂₇H₄₄N₁₀O₆
分子量:604.70

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

Antipain 構造式

CAS 番号: 37691-11-5

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

HY-127034
Antipain dihydrochloride

Ser/Thr Protease Inhibitor

生物活性

製品説明

DNA/RNA Synthesis アイソフォーム固有の製品をすべて表示 :

体内実験

The intact, cycling female mice received subcutaneous injections of Antipain (3 mg) for 16 days, their uteri shows significant diminution in weight and total DNA when compared to untreated controls^[4].
Antipain (100 μg/g body wt; i.p.; at 12h intervals from 0 to 120 h or 240 to 360 h) shows inhibitory effect on Urethane-induced lung neoplasia in mice^[5].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

化学情報

CAS 番号 37691-11-5
分子量 604.70
分子式 C₂₇H₄₄N₁₀O₆
SMILES

OC([C@@H](NC(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(NC(C([H])=O)CCCNC(N)=N)=O)=O)=O)CC1=CC=CC=C1)=O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (274 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. DiPaolo JA, et al. Antipain inhibits N-methyl-N'-nitro-N-nitrosoguanidine-induced transformation and increases chromosomal aberrations. Proc Natl Acad Sci U S A. 1980 Nov;77(11):6649-53. [Content Brief]

[2]. Suda H,et al. Antipain, a new protease inhibitor isolated from actinomycetes. J Antibiot (Tokyo). 1972 Apr;25(4):263-6. [Content Brief]

[3]. Sudha VT, et al. Identification of a serine protease as a major allergen (Per a 10) of Periplaneta americana. Allergy. 2008 Jun;63(6):768-76. [Content Brief]

[4]. Nomura T, et al. Inhibiting effects of antipain on urethane-induced lung neoplasia in mice. Br J Cancer. 1980;42(4):624‐626. [Content Brief]

[5]. Katz J, et al. Antipain and leupeptin restrict uterine DNA synthesis and function in mice. Proc Natl Acad Sci U S A. 1977;74(9):3754‐3757. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

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分子量分子量

希釈計算機

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濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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