Atalaphyllidine
Atalaphyllidine is a natural product. Atalaphyllidine can be isolated from the stem bark of Glycosmis chlorosperma. Atalaphyllidine inhibits DYRK1A kinase activity with an IC50 of 2.2 μM. Atalaphyllidine can be used in the research of neurodegenerative diseases.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 57959-88-3
- 分子式: C18H15NO4
- 分子量:309.32
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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DYRK1A 2.2 μM (IC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
6.98 μM
Compound: 9
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Antiproliferative activity against human A549 cells after 3 days by alamar blue assay
Antiproliferative activity against human A549 cells after 3 days by alamar blue assay
|
[PMID: 10217715] |
Atalaphyllidine (30 min) inhibits DYRK1A kinase activity with an IC50 of 2.2 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 57959-88-3
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分子量 309.32
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分子式 C18H15NO4
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SMILES
O=C1C2=C(NC3=C4C=CC(C)(C)OC4=CC(O)=C13)C(O)=CC=C2
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)