BMS 186318
BMS 186318 is an HIV protease inhibitor. BMS 186318 exhibits better anti-HIV efficacy when used in combination with reverse transcriptase inhibitors such as Stavudine (HY-B0116) and other protease inhibitors such as Saquinavir (HY-17007). BMS 186318 can be used in antiviral research.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 161302-40-5
- 分子式: C36H54N4O9
- 分子量:686.84
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| CEM-SS | ED50 |
0.1 μM
Compound: 10n
|
Inhibitory activity against HIV-1 virus replication as determined by an XTT endpoint by 50%
Inhibitory activity against HIV-1 virus replication as determined by an XTT endpoint by 50%
|
[PMID: 8642558] |
| H9 | CC50 |
>100 μM
Compound: 10n
|
Inhibitory activity against human T cell lymphoma (H9) growth by 50 %.
Inhibitory activity against human T cell lymphoma (H9) growth by 50 %.
|
[PMID: 8642558] |
化学情報
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CAS 番号 161302-40-5
-
分子量 686.84
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分子式 C36H54N4O9
-
SMILES
CC(C)(C)OC(N[C@@H](CC1=CC=CC=C1)[C@H](O)CNC[C@@H](O)[C@H](CC2=CC=C(OCC(N3CCOCC3)=O)C=C2)NC(OC(C)(C)C)=O)=O
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)