BRD32048
Based on 1 Customer Validation
BRD32048 is a direct binder of ETV1 with a KD of 17.1 μM. BRD32048 modulates both ETV1-mediated transcriptional activity and invasion of ETV1-driven cancer cells. BRD32048 inhibits ETV1 acetylation and promotes its degradation. BRD32048 acts as a top candidate ETV1 perturbagen.
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- 純度 : 99.69%
- CAS 番号: 433694-46-3
- 分子式: C16H22N6O
- 分子量:314.39
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保管条件:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
DNA/RNA Synthesis アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
化学情報
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CAS 番号 433694-46-3
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性状 Solid
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分子量 314.39
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分子式 C16H22N6O
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Color White to off-white
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SMILES
NC1=NC(CN2CCCCC2)=NC(NC3=CC=C(OC)C=C3)=N1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
体外:
DMSO : 125 mg/mL (397.60 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (267 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.1808 mL | 15.9038 mL | 31.8076 mL | 79.5191 mL |
| 5 mM | 0.6362 mL | 3.1808 mL | 6.3615 mL | 15.9038 mL | |
| 10 mM | 0.3181 mL | 1.5904 mL | 3.1808 mL | 7.9519 mL | |
| 15 mM | 0.2121 mL | 1.0603 mL | 2.1205 mL | 5.3013 mL | |
| 20 mM | 0.1590 mL | 0.7952 mL | 1.5904 mL | 3.9760 mL | |
| 25 mM | 0.1272 mL | 0.6362 mL | 1.2723 mL | 3.1808 mL | |
| 30 mM | 0.1060 mL | 0.5301 mL | 1.0603 mL | 2.6506 mL | |
| 40 mM | 0.0795 mL | 0.3976 mL | 0.7952 mL | 1.9880 mL | |
| 50 mM | 0.0636 mL | 0.3181 mL | 0.6362 mL | 1.5904 mL | |
| 60 mM | 0.0530 mL | 0.2651 mL | 0.5301 mL | 1.3253 mL | |
| 80 mM | 0.0398 mL | 0.1988 mL | 0.3976 mL | 0.9940 mL | |
| 100 mM | 0.0318 mL | 0.1590 mL | 0.3181 mL | 0.7952 mL |