CD12681
CD12681 (compound 14) is a potent and selective RORγ inverse agonist with IC50 of 19 nM and 10 nM for RORγ GAL4 and CD4-IL-17 cells, respectively. CD12681 decreases the IL-17 inflammatory cell recruitment. CD12681 has the potential for the research of psoriasis.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1952239-59-6
- 分子式: C25H33N3O4S
- 分子量:471.61
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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RORγ |
CD12681 (compound 14) shows inhibition with IC50s of 44, >25, 9 µM for CYP 3A4, CYP 2D6, hERG, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1952239-59-6
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分子量 471.61
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分子式 C25H33N3O4S
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SMILES
O=S(C1=CC(NC(N2CC3CCOCC3)=O)=C2C=C1)(N(C4=CC=C(C)C=C4C)CC(C)C)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
CD12681 関連分類
HY-111366 関連分類
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