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製品番号: HY-187674

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Dicranin

Dicranin is a 15-lipoxygenase (15-LOX) inhibitor and bacterial agent. Dicranin inhibits the dioxygenation reaction of polyenoic fatty acids by irreversibly binding to lipoxygenase. Dicranin can be isolated from the phospholipids of Philonotis fontana, Leptodontium paradoxum, and Dicranum scoparium. Dicranin can be used in studies related to Gram-positive bacterial infections.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 61481-30-9
分子式: C₁₈H₂₆O₂
分子量:274.40

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Dicranin 構造式

CAS 番号: 61481-30-9

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

IC₅₀ & Target

^[1]

15-LOX

Lipoxygenase アイソフォーム固有の製品をすべて表示 :

体外実験

OthersBacterial Infection

Others

Dicranin (0.36-3.6 μM) potently inhibits soybean 15-lipoxygenase, achieving 100% inhibition at 3.6 μM and 37% inhibition at 0.36 μM^[2].

Bacterial Infection

Dicranin (10-1000 μg/disc) inhibits growth of Gram-positive bacteria (Bacillus stearothermophilus, Bacillus cereus, Bacillus subtilis, Staphylococcus aureus, Streptococcus faecalis) in disc diffusion assays, with the strongest activity against Streptococcus faecalis (inhibition down to 10 μg/disc), and no activity against tested Gram-negative bacteria at 1000 μg/disc^[2].
Dicranin (10-200 μg/mL; up to 24 h) acts as a bactericide against Bacillus cereus (down to 150 μg/mL) and Bacillus stearothermophilus (at 200 μg/mL), with time-dependent bactericidal/bacteriostatic effects at intermediate concentrations, weak growth inhibition against Bacillus stearothermophilus at 10 μg/mL, no activity against Bacillus cereus at 10 μg/mL^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Gram Staining of Tissue Sections

化学情報

CAS 番号 61481-30-9
分子量 274.40
分子式 C₁₈H₂₆O₂
SMILES

CC/C=C\C/C=C\C/C=C\CC#CCCCCC(O)=O
Structure Classification
- Ketones, Aldehydes, Acids
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Roy Chowdhuri S, et al. "Dicranin" in the Membrane Phospholipids of a Dicranaceae and Pottiaceae Moss Member of the Eastern Himalayan Biodiversity Hotspot. Lipids. 2018 May;53(5):539-545.

[2]. Borel C, et al. Dicranin, an antimicrobial and 15-lipoxygenase inhibitor from the moss Dicranum scoparium. Journal of natural products. 1993 Jul;56(7):1071-7.

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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生物活性
- 製品説明
- IC₅₀ & Target
- 体外実験
化学情報
純度とドキュメンテーション
参考文献

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Dicranin

Lipoxygenase アイソフォーム固有の製品をすべて表示

生物活性

製品説明

IC50 & Target

体外実験

化学情報

純度とドキュメンテーション

参考文献

Calculators

Help & FAQs

Dicranin 関連分類

HY-187674 関連分類

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Keywords

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