Ethisterone
Based on 1 publication(s) in Google Scholar
Ethisterone (Pregneninolone; 17α-Ethynyltestosterone) is a synthetic steroidal estrogen, is an orally active steroidal contraceptive agent. Ethisterone has almost no effect on the phagocytic activity of the reticuloendothelial system in male guinea pigs, while in utero exposure can induce abnormalities in the urogenital system of offspring.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.02%
- CAS 番号: 434-03-7
- 分子式: C21H28O2
- 分子量:312.45
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
MedChemExpress(MCE)の使用を引用している文献 Ethisterone
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生物活性
Ethisterone acts as an inducer of urogenital abnormalities, with in utero exposure linked to increased offspring urogenital abnormality prevalence, higher risk with earlier exposure onset[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Guinea pigs (Male)[1]
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Dosage:0.5 mg
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Administration:i.m.; daily; 2 weeks; 4 weeks
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Result:Contained a moderate number of dye granules in macrophages of the spleen, liver, and lymph nodes.
Showed vital staining appearances closely resembling those of control animals.
化学情報
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CAS 番号 434-03-7
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性状 Solid
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分子量 312.45
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分子式 C21H28O2
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Color Light yellow to yellow
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SMILES
C[C@@]1([C@]2(O)C#C)[C@](CC2)([H])[C@@](CCC3=CC4=O)([H])[C@]([C@]3(CC4)C)([H])CC1
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別名
Ethisterone; 17α-Ethynyltestosterone; エチステロン
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Publications (1)
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Journal Impact Factor
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Most Recent
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Commun Biol
5α-Reductase underscores the development of pectoral fin breeding tubercles in zebrafish. [Abstract]2026 Apr 24;9(1):873. PMID: 42032132
溶剤 & 溶解度
Ethanol : 1 mg/mL (3.20 mM; ultrasonic and warming and heat to 60°C)
DMSO : < 1 mg/mL (insoluble or slightly soluble)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (274 KB)
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SDS (419 KB)
- English - EN (419 KB)
- Français - FR (419 KB)
- Deutsch - DE (419 KB)
- Norwegian - NO (419 KB)
- Español - ES (419 KB)
- Swedish - SV (419 KB)
- Italian - IT (419 KB)
- Korean - KR (419 KB)
- Portuguese - PT (419 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Ethanol | 1 mM | 3.2005 mL | 16.0026 mL | 32.0051 mL | 80.0128 mL |
- Ethisterone
- 434-03-7
- Pregneninolone
- 17α-Ethynyltestosterone
- Estrogen Receptor/ERR
- male guinea pigs
- diabetic pregnancies
- infertility
- amenorrhoea
- progestogen sex hormone
- female reproductive function
- reticulo-endothelial system
- male sexual/social function
- spontaneous abortion
- urogenital abnormalities
- Inhibitor
- inhibitor
- inhibit