HE-S2
HE-S2 is an antibody-drug conjugate triggering a potent antitumor immune response. HE-S2 acts by blocking the PD-1/PD-L1 interaction and activating the Toll-like receptor 7/8 (TLR7/8) signaling pathway. HE-S2 has remarkable antitumor activity.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2939851-67-7
- 分子式: C38H45N9O6S2
- 分子量:787.95
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
Drug-Linker Conjugates for ADC アイソフォーム固有の製品をすべて表示
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生物活性
PD-1/PD-L1 and TLR7/8 [1]
HE-S2 (10 ng; 30 min) effectively targets and binds with PD-L1in MC38 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2939851-67-7
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分子量 787.95
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分子式 C38H45N9O6S2
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SMILES
C[C@H](COC(NC1=CC=C(C[N+](C)(C)CC2=CC=C(CC3=CC=C(N=C(N)N=C4NCCCC)C4=N3)C=C2)C=C1)=O)SSC5=NC=C([N+]([O-])=O)C=C5.[H]C([O-])=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)