HSR-609
HSR-609 is an orally active amphoteric antiallergic agent. HSR-609 has a high affinity for histamine H1-receptor in the guinea pig cerebral cortex. HSR-609 inhibits allergic airway hyperresponsiveness to Acetylcholine. HSR-609 shows poor ability to penetrate into the CNS in mice and guinea pigs.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 161522-25-4
- 分子式: C21H21FN2O3
- 分子量:368.40
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Histamine Receptor アイソフォーム固有の製品をすべて表示
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生物活性
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H1 Receptor |
化学情報
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CAS 番号 161522-25-4
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分子量 368.40
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分子式 C21H21FN2O3
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SMILES
O=C(O)CCN1CC/C(CC1)=C2C3=CC=C(F)C=C3OCC4=CC=CN=C4\2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. M Kakiuchi, et al. Studies on the novel antiallergic agent HSR-609: its penetration into the central nervous system in mice and guinea pigs and its selectivity for the histamine H1-receptor. Jpn J Pharmacol. 1997 Apr;73(4):291-8. [Content Brief]
[2]. K Musoh, et al. Effect of a novel anti-allergic agent, HSR-609, on antigen-induced airway hyperresponsiveness in mice. Pharmacology. 2000 Aug;61(2):70-7. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
HSR-609 関連分類
HY-114724 関連分類
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