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United States

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Total: USD 0.00 Checkout

製品番号: HY-P992543

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IBI3011

IBI3011 is a humanized anti-IL1RAP monoclonal antibody. IBI3011 inhibits inflammatory pathways driven by IL1, IL33, and IL36. IBI3011 can be used in research related to inflammatory and immune diseases, such as gout and arthritis.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

IBI3011 構造式

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性
- 製品説明
- Species Reactivity
- IC₅₀ & Target
- 体外実験
- 体内実験
- Target
- Conjugated
- アプリケーション
化学情報
純度とドキュメンテーション
参考文献
Calculators
Help & FAQs
関連分類
Bioz

生物活性

製品説明

Species Reactivity

Human

IC₅₀ & Target

^[1]

IL-1

IL33

IL36

Interleukin Related アイソフォーム固有の製品をすべて表示 :

体外実験

Innate Immunity

IBI3011 exhibits high affinity for human and cynomolgus monkey IL1RAP proteins at both the protein and cellular levels, but shows no affinity for mouse IL1RAP protein^[1].
IBI3011 inhibits the secretion of inflammatory cytokines TNFα and IFNγ by peripheral blood mononuclear cells (PBMCs) stimulated with IL1α/β, IL33, and IL36α/β/γ^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Target

IL-1RAP

Conjugated

Unconjugated

アプリケーション

ELISA, FACS, Functional assay

化学情報

SMILES

[IBI3011]
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

Inhibitory Antibodies User Guide (603 KB)

参考文献

[1]. Tian H, et al. IBI3011, a Humanized anti-IL1RAP Monoclonal Antibody, Inhibits IL1, IL33, IL36-driven Inflammation Pathway, and Attenuates Inflammation in Preclinical Inflammatory Disease Model [abstract]. Arthritis Rheumatol. 2025; 77 (suppl 9).

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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