IKK2-IN-3
Based on 1 Customer Validation
IKK2-IN-3 is an IKK2 inhibitor with an IC50 value of 0.075 μM. IKK2-IN-3 can be used for the research of cancer, rheumatoid arthritis, chronic obstructive pulmonary disease (COPD).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.0%
- CAS 番号: 916985-21-2
- 分子式: C22H21N3O6S2
- 分子量:487.55
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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IKK2 0.075 μM (IC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | IC50 |
>30000 nM
Compound: 39
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Antiproliferative activity against human HCT116 cells after 3 days by methylene blue stain technique
Antiproliferative activity against human HCT116 cells after 3 days by methylene blue stain technique
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[PMID: 19097784] |
IKK2-IN-3 (Compound 8) inhibits IKK2 with an IC50 of 0.075 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 916985-21-2
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性状 Solid
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分子量 487.55
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分子式 C22H21N3O6S2
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Color White to off-white
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SMILES
O=C(C1=C(OCC2=CC=C(S(=O)(C)=O)C=C2)C=C(N3C4=CC(OC)=C(OC)C=C4N=C3)S1)N
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 10 mg/mL (20.51 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (274 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0511 mL | 10.2554 mL | 20.5107 mL | 51.2768 mL |
| 5 mM | 0.4102 mL | 2.0511 mL | 4.1021 mL | 10.2554 mL | |
| 10 mM | 0.2051 mL | 1.0255 mL | 2.0511 mL | 5.1277 mL | |
| 15 mM | 0.1367 mL | 0.6837 mL | 1.3674 mL | 3.4185 mL | |
| 20 mM | 0.1026 mL | 0.5128 mL | 1.0255 mL | 2.5638 mL |
IKK2-IN-3 関連分類
HY-111135 関連分類
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