IL-17A modulator-3
Based on 1 Customer Validation
IL-17A modulator-3 (compound 253) is a IL-17A modulator. IL-17A modulator-3 inhibits IL-17A/A with an IC50 value <10 μM. IL-17A modulator-3 can be used for the research of inflammation, cancer and autoimmune disease.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.37%
- CAS 番号: 2467732-95-0
- 分子式: C34H50FN7O4
- 分子量:639.80
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
IC50: <10 μM (IL-17A/A)[1]
化学情報
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CAS 番号 2467732-95-0
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性状 Solid
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分子量 639.80
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分子式 C34H50FN7O4
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Color White to off-white
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SMILES
O=C(C1=CC=NN1C(C)C)N[C@@H]([C@H]2CC[C@H](C)CC2)C(NC3=CC=C([C@H](C)[C@@H](NC(CC)=O)C(N4CCN(C)CC4)=O)C=C3F)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 50 mg/mL (78.15 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.5630 mL | 7.8149 mL | 15.6299 mL | 39.0747 mL |
| 5 mM | 0.3126 mL | 1.5630 mL | 3.1260 mL | 7.8149 mL | |
| 10 mM | 0.1563 mL | 0.7815 mL | 1.5630 mL | 3.9075 mL | |
| 15 mM | 0.1042 mL | 0.5210 mL | 1.0420 mL | 2.6050 mL | |
| 20 mM | 0.0781 mL | 0.3907 mL | 0.7815 mL | 1.9537 mL | |
| 25 mM | 0.0625 mL | 0.3126 mL | 0.6252 mL | 1.5630 mL | |
| 30 mM | 0.0521 mL | 0.2605 mL | 0.5210 mL | 1.3025 mL | |
| 40 mM | 0.0391 mL | 0.1954 mL | 0.3907 mL | 0.9769 mL | |
| 50 mM | 0.0313 mL | 0.1563 mL | 0.3126 mL | 0.7815 mL | |
| 60 mM | 0.0260 mL | 0.1302 mL | 0.2605 mL | 0.6512 mL |