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製品番号: HY-19418

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KRP-101

KRP-101 is a compound that regulates the expression of genes related to lipid metabolism. It is a PPARα agonist that can highly sensitively regulate the expression of genes such as apolipoprotein A-IV, which may be related to lowering serum triglycerides and increasing HDL.

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CAS 番号: 311770-26-0
分子式: C₂₆H₂₆FNO₅
分子量:451.49

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (262 KB)

KRP-101 構造式

CAS 番号: 311770-26-0

容量

価格（税別）

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数量

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

PPAR アイソフォーム固有の製品をすべて表示 :

Cellular Effect

Cell Line	Type	Value	Description	References
CHO-K1	EC₅₀	0.014 μM Compound: 7	Transcriptional activation activity on human T279M-mutant Peroxisome proliferator activated receptor alpha expressed in CHO-K1 cells Transcriptional activation activity on human T279M-mutant Peroxisome proliferator activated receptor alpha expressed in CHO-K1 cells	[PMID: 12951082]
CHO-K1	EC₅₀	0.667 μM Compound: 7	Transcriptional activation activity on human I272F-mutant Peroxisome proliferator activated receptor alpha expressed in CHO-K1 cells Transcriptional activation activity on human I272F-mutant Peroxisome proliferator activated receptor alpha expressed in CHO-K1 cells	[PMID: 12951082]
CHO-K1	EC₅₀	0.00061 μM Compound: 7	Transcriptional activation activity on human Peroxisome proliferator activated receptor alpha expressed in CHO-K1 cells Transcriptional activation activity on human Peroxisome proliferator activated receptor alpha expressed in CHO-K1 cells	[PMID: 12951082]
CHO-K1	EC₅₀	0.61 nM Compound: 7	Transcriptional activation activity on human Peroxisome proliferator activated receptor alpha expressed in CHO-K1 cells Transcriptional activation activity on human Peroxisome proliferator activated receptor alpha expressed in CHO-K1 cells	[PMID: 12951082]
CHO-K1	EC₅₀	0.013 μM Compound: KRP-101	Transactivation of human PPARalpha expressed in CHO-K1 cells Transactivation of human PPARalpha expressed in CHO-K1 cells	[PMID: 22133631]
CHO-K1	EC₅₀	1.92 μM Compound: KRP-101	Transactivation of human PPARdelta expressed in CHO-K1 cells Transactivation of human PPARdelta expressed in CHO-K1 cells	[PMID: 22133631]
CHO-K1	EC₅₀	2.5 μM Compound: KRP-101	Transactivation of human PPARgamma expressed in CHO-K1 cells Transactivation of human PPARgamma expressed in CHO-K1 cells	[PMID: 22133631]

化学情報

CAS 番号 311770-26-0
分子量 451.49
分子式 C₂₆H₂₆FNO₅
SMILES

FC(C=C1)=CC=C1OC(C=C2)=CC=C2CNC(C3=C(C=CC(C[C@H](CC)C(O)=O)=C3)OC)=O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (262 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Highly sensitive upregulation of apolipoprotein A-IV by peroxisome proliferator-activated receptor alpha (PPARalpha) agonist in human hepatoma cells

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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生物活性
- 製品説明
化学情報
純度とドキュメンテーション
参考文献

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KRP-101

PPAR アイソフォーム固有の製品をすべて表示

生物活性

化学情報

純度とドキュメンテーション

参考文献

Calculators

Help & FAQs

KRP-101 関連分類

HY-19418 関連分類