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製品番号: HY-P991699

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Lixarkitug

Name: Lixarkitug
Brand: MedChemExpress
SKU: HY-P991699
Price: 260.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(別名: AZD9829 antibody; INT-020)

カスタマーレビュー

Based on 1 Customer Validation

Lixarkitug (AZD9829 antibody; INT-020) is a humanized IgG1κ antibody targeting IL-3Ra/CD123. Lixarkitug can be conjugated with Samrotecan to form the intact ADC molecule lixarkitug samrotecan (AZD9829), which is used in studies of acute myeloid leukemia (AML). The isotype control corresponding to Lixarkitug is Human IgG1 kappa, Isotype Control (HY-P99001).

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

純度 : 99%
CAS 番号: 3035710-69-8
分子量:146.147 kDa

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Lixarkitug 構造式

CAS 番号: 3035710-69-8

容量

価格（税別）

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数量

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生物活性
- 製品説明
- Isotype
- Recommend Isotype Controls
- Species Reactivity
- IC₅₀ & Target
- 体外実験
- 遺伝子ID
- アクセッション番号
- Conjugated
- Reconsititution
- Format
- アプリケーション
化学情報
純度とドキュメンテーション
参考文献
Calculators
Help & FAQs
関連分類
Bioz

生物活性

製品説明

Lixarkitug (AZD9829 antibody; INT-020) is a humanized IgG1κ antibody targeting IL-3Ra/CD123. Lixarkitug can be conjugated with Samrotecan to form the intact ADC molecule lixarkitug samrotecan (AZD9829), which is used in studies of acute myeloid leukemia (AML)^[1]^[2]. The isotype control corresponding to Lixarkitug is Human IgG1 kappa, Isotype Control (HY-P99001).

Isotype

Human IgG1 kappa

Recommend Isotype Controls

Human IgG1 kappa, Isotype Control

Species Reactivity

Human

IC₅₀ & Target

IL-3

Interleukin Related アイソフォーム固有の製品をすべて表示 :

体外実験

Lixarkitug is a monoclonal antibody defined by a 449-amino-acid heavy chain and 219-amino-acid light chain, with a conjugated form (lixarkitug samrotecan) sharing identical chain lengths.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

遺伝子ID

3563 [NCBI]

アクセッション番号

P26951

Conjugated

Unconjugated

Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.

Format

IgG1-kappa

アプリケーション

ELISA, FACS, Functional assay

化学情報

CAS 番号 3035710-69-8
性状 Liquid
分子量 146.147 kDa
Color Colorless to light yellow
SMILES

N/A
別名

AZD9829 antibody; INT-020
輸送条件

Shipping with dry ice.
Formulation

Please refer to the lot-specific COA for specific buffer information.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (257 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Inhibitory Antibodies User Guide (603 KB)

参考文献

[1]. WHO Drug Information, Vol. 39, No. 2, 2025

[2]. Dutta D, et al. First disclosure of AZD9829, a TOP1i-ADC targeting CD123: Promising preclinical activity in AML models with minimal effect on healthy progenitors[J]. Blood, 2023, 142: 5957.

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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