LS24-16
LS24-16 is a carbonic anhydrase (CA) IX enzyme inhibitor (Ki ≤ 1.6 nM versus human CA IX; Kd = 0.40 nM). LS24-16 inhibits carbon dioxide hydration by binding to the catalytic zinc site and displacing the zinc-bound water with its deprotonated sulfamate amino group. LS24-16 competes with fluorescent CA IX probes for binding to CA IX on hypoxic cells and remains stable under the tested stress conditions. LS24-16 can be used for solid tumor research.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2352790-85-1
- 分子式: C13H13NO4S
- 分子量:279.31
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
生物活性
製品説明
IC50 & Target
[1]|
hCA IX 0.40 nM (Kd) |
CA VII 6.1 nM (Kd) |
CA XIII 6.2 nM (Kd) |
体外実験
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 2352790-85-1
-
分子量 279.31
-
分子式 C13H13NO4S
-
SMILES
NS(OC1=CC=CC=C1OCC2=CC=CC=C2)(=O)=O
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
LS24-16 関連分類
HY-190902 関連分類
Powered by Bioz