LY-510929
LY-510929 is a compound that induces left ventricular hypertrophy (LVH). Related studies have identified the relevant conditions in which LY-510929 may induce LVH by measuring multiple markers and using multiple techniques.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 401789-93-3
- 分子式: C26H25NO5S
- 分子量:463.55
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CV-1 | EC50 |
0.004 μM
Compound: 7
|
Transactivation of GAL4-fused Homo sapiens (human) PPARgamma DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter gene assay
Transactivation of GAL4-fused Homo sapiens (human) PPARgamma DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter gene assay
|
10.1007/s00044-012-0003-4 |
| CV-1 | EC50 |
0.009 μM
Compound: 7
|
Transactivation of GAL4-fused Homo sapiens (human) PPARalpha DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter gene assay
Transactivation of GAL4-fused Homo sapiens (human) PPARalpha DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter gene assay
|
10.1007/s00044-012-0003-4 |
| CV-1 | EC50 |
4 nM
Compound: 2
|
Transcriptional activation of reporter assay by PPAR gamma receptor in CV-1 cells
Transcriptional activation of reporter assay by PPAR gamma receptor in CV-1 cells
|
[PMID: 15115385] |
| CV-1 | EC50 |
9 nM
Compound: 2
|
Transcriptional activation of reporter assay by human Peroxisome proliferator activated receptor alpha in CV-1 cells
Transcriptional activation of reporter assay by human Peroxisome proliferator activated receptor alpha in CV-1 cells
|
[PMID: 15115385] |
化学情報
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CAS 番号 401789-93-3
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分子量 463.55
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分子式 C26H25NO5S
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SMILES
CC(OC(C1=CC=CS1)=N2)=C2CCOC3=CC=C(C=C3)C[C@@](C)(C(O)=O)OC4=CC=CC=C4
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輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)