MEY-003
MEY-003 is an Autotaxin(ATX) inhibitor with EC50s of 460 nM and 1.09 μM for hATX-β and hATX-ɣ (analysis with LPC18:1). MEY-003 behaves as a non-competitive inhibitor with K iof 432 nM. MEY-003 can be used for targeted ATX-related disease research .
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 3047891-88-0
- 分子式: C22H21NO4
- 分子量:363.41
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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Autotaxin |
MEY-003 (10 μM, 30 min) blocks lysophosphatidic acid (LPA) signaling, and reduces LPA1 receptor internalization in HeLa cell[1].
MEY-003 (100 μM, 0-24 h) shows no cytotoxicity effects in HeLa and HEK293 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:HeLa and HEK293 cells
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Concentration:100 μM
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Incubation Time:0-24 h
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Result:Showed non-cytotoxic after prolonged treatment (up to 24 h) at 100 μM with HeLa cells or HEK293 cells.
化学情報
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CAS 番号 3047891-88-0
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分子量 363.41
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分子式 C22H21NO4
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SMILES
OC1=C2C(OC(C3=CN(CCCCC)C4=C3C=CC=C4)=CC2=O)=CC(O)=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
MEY-003 関連分類
HY-149716 関連分類
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