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製品番号: HY-125163

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MM 47755

Name: MM 47755
Brand: MedChemExpress
SKU: HY-125163
Price: 638.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(別名: 8-O-Methyltetrangomycin; 6-Deoxy-8-O-methylrabelomycin)

MM 47755 (8-O-Methyltetrangomycin; 6-Deoxy-8-O-methylrabelomycin) is an antibiotic with antibacterial activity. MM 47755 can be isolated from Streptomyces.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 117620-87-8
分子式: C₂₀H₁₆O₅
分子量:336.34

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

MM 47755 構造式

CAS 番号: 117620-87-8

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

MM 47755 (8-O-Methyltetrangomycin; 6-Deoxy-8-O-methylrabelomycin) is an antibiotic with antibacterial activity. MM 47755 can be isolated from Streptomyces^[1].

Antibiotic アイソフォーム固有の製品をすべて表示 :

Cellular Effect

Cell Line	Type	Value	Description	References
HepG2	IC₅₀	>100 μM Compound: 4	Cytotoxicity against human HepG2 cells after 2 days by CellTiter-Glo assay Cytotoxicity against human HepG2 cells after 2 days by CellTiter-Glo assay	[PMID: 23025282]
HepG2	IC₅₀	18.5 μM Compound: 4	Antiplasmodial activity against luciferase-expressing sporozoite of Plasmodium berghei ANKA infected in human HepG2 cells assessed as reduction of parasite load after 2 days Antiplasmodial activity against luciferase-expressing sporozoite of Plasmodium berghei ANKA infected in human HepG2 cells assessed as reduction of parasite load after 2 days	[PMID: 23025282]
M14	IC₅₀	9.7 μM Compound: 16	Cytotoxicity against human M14 cells after 72 hrs by MTS assay Cytotoxicity against human M14 cells after 72 hrs by MTS assay	[PMID: 26335269]
MDA-MB-468	IC₅₀	27 μM Compound: 16	Cytotoxicity against human MDA-MB-468 cells after 72 hrs by MTS assay Cytotoxicity against human MDA-MB-468 cells after 72 hrs by MTS assay	[PMID: 26335269]
NCI-H226	IC₅₀	4.6 μM Compound: 16	Cytotoxicity against human NCI-H226 cells after 72 hrs by MTS assay Cytotoxicity against human NCI-H226 cells after 72 hrs by MTS assay	[PMID: 26335269]
SF-295	IC₅₀	17 μM Compound: 16	Cytotoxicity against human SF295 cells after 72 hrs by MTS assay Cytotoxicity against human SF295 cells after 72 hrs by MTS assay	[PMID: 26335269]
SF-539	IC₅₀	10 μM Compound: 16	Cytotoxicity against human SF539 cells after 72 hrs by MTS assay Cytotoxicity against human SF539 cells after 72 hrs by MTS assay	[PMID: 26335269]

体外実験

MM 47755 has inhibitory activity against Staphylococcus aureus Smith, S. aureus MS9610 (multi-resistant), Micrococcus luteus PCI 1001, Bacillus subtilis NRRLB-558 with MIC values of 12. 5, 12. 5, 25, 12. 5 μg/mL respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

化学情報

CAS 番号 117620-87-8
分子量 336.34
分子式 C₂₀H₁₆O₅
SMILES

O=C1C[C@](C)(O)CC(C1=C2C3=O)=CC=C2C(C4=C3C=CC=C4OC)=O
別名

8-O-Methyltetrangomycin; 6-Deoxy-8-O-methylrabelomycin
Structure Classification
- Antibiotics
- Other Antibiotics
Initial Source
- Microorganisms
Streptomyces
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (271 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Shigihara Y, et al. 6-Deoxy-8-O-methylrabelomycin and 8-O-methylrabelomycin from a Streptomyces species. J Antibiot (Tokyo). 1988 Sep;41(9):1260-4. [Content Brief]

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濃度 _(終了) 濃度 _(終了)

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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