Neoschaftoside
Based on 1 Customer Validation
Neoschaftoside is a C-glycosyl flavonoid EGFR modulator, antifungal agent, and piercing-sucking stimulant for planthoppers. Neoschaftoside forms stable EGFR complexes, restricts global protein movement, enhances related dynamic processes, and inhibits tumor progression. Neoschaftoside interacts with EGFR core regulatory genes associated with lung cancer. Neoschaftoside inhibits Botrytis cinerea. Neoschaftoside can be used in research related to lung cancer and Botrytis cinerea infections.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.04%
- CAS 番号: 61328-41-4
- 分子式: C26H28O14
- 分子量:564.49
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保管条件:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
EGFR アイソフォーム固有の製品をすべて表示
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生物活性
Neoschaftoside binds with high affinity to the ATP-binding cleft of the purified EGFR tyrosine kinase domain (PDB ID: 4ZAU), as evidenced by a Glide docking score of -10.765 and a Glide energy of -63.293 kcal/mol, forming multiple stabilizing hydrogen bonds and hydrophobic contacts[1].
Neoschaftoside exists in mixed C-glycosylflavones extracted from elicitor-treated Colobanthus quitensis, and the mixture (75 μg/mL extract concentration) inhibits radial mycelial growth of Botrytis cinerea[2].
Neoschaftoside induces intense stylet probing behavior of Nilaparvata lugens, Sogatella furcifera and Laodelphax striatellus on artificial sucrose medium[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 61328-41-4
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性状 Solid
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分子量 564.49
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分子式 C26H28O14
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Color White to off-white
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SMILES
OC1=C([C@@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)CO)C(O)=C(C(C=C(C3=CC=C(C=C3)O)O4)=O)C4=C1[C@@H]5[C@@H]([C@H]([C@H](CO5)O)O)O
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
純度とドキュメンテーション
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データシート (284 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Neoschaftoside 関連分類
HY-N10103 関連分類
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