Oxynitidine
Oxynitidine is an HBV inhibitor (ID50=30.8 µg/mL), which can effectively inhibit the DNA replication activity of HBV. Oxynitidine can be used in the study of viral infections.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 548-31-2
- 分子式: C21H17NO5
- 分子量:363.36
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | GI50 |
39 μM
Compound: 1
|
Growth inhibition of human A549 cells incubated for 72 hrs by MTT assay
Growth inhibition of human A549 cells incubated for 72 hrs by MTT assay
|
[PMID: 31176097] |
| A549 | GI50 |
39.38 μM
Compound: 6
|
Growth inhibition of human A549 cells after 72 hrs by MTT assay
Growth inhibition of human A549 cells after 72 hrs by MTT assay
|
[PMID: 30336023] |
| CCRF-CEM | GI50 |
26.52 μM
Compound: 6
|
Growth inhibition of human CCRF-CEM cells after 72 hrs by MTT assay
Growth inhibition of human CCRF-CEM cells after 72 hrs by MTT assay
|
[PMID: 30336023] |
| DU-145 | GI50 |
64 μM
Compound: 1
|
Growth inhibition of human DU145 cells incubated for 72 hrs by MTT assay
Growth inhibition of human DU145 cells incubated for 72 hrs by MTT assay
|
[PMID: 31176097] |
| DU-145 | GI50 |
64.23 μM
Compound: 6
|
Growth inhibition of human DU145 cells after 72 hrs by MTT assay
Growth inhibition of human DU145 cells after 72 hrs by MTT assay
|
[PMID: 30336023] |
| HCT-116 | GI50 |
74 μM
Compound: 1
|
Growth inhibition of human HCT116 cells incubated for 72 hrs by MTT assay
Growth inhibition of human HCT116 cells incubated for 72 hrs by MTT assay
|
[PMID: 31176097] |
| HCT-116 | GI50 |
74.79 μM
Compound: 6
|
Growth inhibition of human HCT116 cells after 72 hrs by MTT assay
Growth inhibition of human HCT116 cells after 72 hrs by MTT assay
|
[PMID: 30336023] |
| Huh-7 | GI50 |
>100 μM
Compound: 6
|
Growth inhibition of human HuH7 cells after 72 hrs by MTT assay
Growth inhibition of human HuH7 cells after 72 hrs by MTT assay
|
[PMID: 30336023] |
| MCF7 | GI50 |
31 μM
Compound: 1
|
Growth inhibition of human MCF7 cells incubated for 72 hrs by MTT assay
Growth inhibition of human MCF7 cells incubated for 72 hrs by MTT assay
|
[PMID: 31176097] |
化学情報
-
CAS 番号 548-31-2
-
分子量 363.36
-
分子式 C21H17NO5
-
SMILES
O=C1C2=CC(OC)=C(C=C2C3=C(N1C)C4=CC5=C(OCO5)C=C4C=C3)OC
-
Structure Classification
-
Initial Source
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)