Penipanoid C
Penipanoid C (Compound 9) is a BRD4 inhibitor. Penipanoid C can be isolated from marine sediment-derived fungus Penicillium paneum SD-44. Penipanoid C has anti-inflammatory activity and cytotoxic activity against the SMMC-7721 cells. Penipanoid C can be used for inflammatory diseases research.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1442381-95-4
- 分子式: C15H10N2O3
- 分子量:266.25
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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BRD4 |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | IC50 |
>50 μM
Compound: 3a
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Cytotoxicity against human HepG2 cells assessed as inhibition of proliferation incubated for 72 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as inhibition of proliferation incubated for 72 hrs by MTT assay
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[PMID: 34237623] |
化学情報
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CAS 番号 1442381-95-4
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分子量 266.25
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分子式 C15H10N2O3
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SMILES
O=C1N=C(C(C2=CC=C(C=C2)O)=O)NC3=C1C=CC=C3
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Structure Classification
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Initial Source
Penicillium oxalicum
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Chen S, et al. Marine natural product-inspired discovery of novel BRD4 inhibitors with anti-inflammatory activity. Eur J Med Chem. 2025 Feb 15;284:117193. [Content Brief]
[2]. Li CS, et al. Triazole and dihydroimidazole alkaloids from the marine sediment-derived fungus Penicillium paneum SD-44. J Nat Prod. 2011 May 27;74(5):1331-4. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Penipanoid C 関連分類
HY-N16067 関連分類
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