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製品番号: HY-158208

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PMMB276

PMMB276 is a potent inhibitor of β-tubulin isotype III (Tubb3) polymerization and induced apoptosis. PMMB276 plays an important role in cancer research.

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CAS 番号: 2209036-28-0
分子式: C₃₁H₃₄O₆S₂
分子量:566.73

保管条件:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

PMMB276 構造式

CAS 番号: 2209036-28-0

容量

価格（税別）

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Amount: USD 0.00

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

PMMB276 is a potent inhibitor of β-tubulin isotype III (Tubb3) polymerization and induced apoptosis. PMMB276 plays an important role in cancer research^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	16.37 μM Compound: 1c	Antiproliferative activity against human A549 cells after 24 hrs by MTT assay Antiproliferative activity against human A549 cells after 24 hrs by MTT assay	[PMID: 29268130]
HEK-293T	IC₅₀	88.83 μM Compound: 1c	Antiproliferative activity against human 293T cells after 24 hrs by MTT assay Antiproliferative activity against human 293T cells after 24 hrs by MTT assay	[PMID: 29268130]
HeLa	IC₅₀	3.14 μM Compound: 1c	Antiproliferative activity against human HeLa cells after 24 hrs by MTT assay Antiproliferative activity against human HeLa cells after 24 hrs by MTT assay	[PMID: 29268130]
HepG2	IC₅₀	5.37 μM Compound: 1c	Antiproliferative activity against human HepG2 cells after 24 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 24 hrs by MTT assay	[PMID: 29268130]
L02	IC₅₀	116.2 μM Compound: 1c	Antiproliferative activity against human LO2 cells after 24 hrs by MTT assay Antiproliferative activity against human LO2 cells after 24 hrs by MTT assay	[PMID: 29268130]
MDA-MB-231	IC₅₀	17.67 μM Compound: 1c	Antiproliferative activity against human MDA231 cells after 24 hrs by MTT assay Antiproliferative activity against human MDA231 cells after 24 hrs by MTT assay	[PMID: 29268130]

化学情報

CAS 番号 2209036-28-0
性状 Solid
分子量 566.73
分子式 C₃₁H₃₄O₆S₂
Color Brown to reddish brown
SMILES

O=C(C1=C(C=CC(O)=C12)O)C=C([C@@H](C/C=C(C)/C)OC(CCCC[C@H]3SC(SCC3)C4=CC=CC=C4)=O)C2=O
輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (266 KB)
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Hongwei Han, et al. A modified natural small molecule inhibits triple-negative breast cancer growth by interacting with Tubb3. Phytomedicine. 2024 Apr:126:154894. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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生物活性
- 製品説明
化学情報
純度とドキュメンテーション
参考文献

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PMMB276

High-Throughput Bioactive Compound Library

生物活性

化学情報

純度とドキュメンテーション

参考文献

Calculators

Help & FAQs

PMMB276 関連分類

HY-158208 関連分類