Progesterone-d9
Based on 1 Customer Validation
Progesterone-d9 is the deuterium labeled Progesterone. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.66%
- CAS 番号: 15775-74-3
- 分子式: C21H21D9O2
- 分子量:323.52
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Endogenous Metabolite アイソフォーム固有の製品をすべて表示
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生物活性
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
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CAS 番号 15775-74-3
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非標識Cas 57-83-0
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性状 Solid
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分子量 323.52
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分子式 C21H21D9O2
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Color White to light yellow
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SMILES
C[C@]12[C@]([H])([C@@]3(CC([2H])(C4=C(C(C([2H])(C[C@@]4([C@]3(CC2)[H])C)[2H])=O)[2H])[2H])[H])CC[C@@]1(C(C([2H])([2H])[2H])=O)[2H]
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別名
Pregn-4-ene-3,20-dione-d9
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 25 mg/mL (77.27 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (277 KB)
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SDS (419 KB)
- English - EN (419 KB)
- Français - FR (419 KB)
- Deutsch - DE (419 KB)
- Norwegian - NO (419 KB)
- Español - ES (419 KB)
- Swedish - SV (419 KB)
- Italian - IT (419 KB)
- Korean - KR (419 KB)
- Portuguese - PT (419 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Schindler AE, et al. Classification and pharmacology of progestins. Maturitas. 2003 Dec 10;46 Suppl 1:S7-S16. [Content Brief]
[3]. Zava DT, et al. Estrogen and progestin bioactivity of foods, herbs, and spices. Proc Soc Exp Biol Med. 1998 Mar;217(3):369-78. [Content Brief]
[4]. Komesaroff PA, et al. Effects of wild yam extract on menopausal symptoms, lipids and sex hormones in healthy menopausal women. Climacteric. 2001 Jun;4(2):144-50. [Content Brief]
[5]. Girling JE, et al. Progesterone, but not estrogen, stimulates vessel maturation in the mouse endometrium. Endocrinology. 2007 Nov;148(11):5433-41. Epub 2007 Aug 9. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0910 mL | 15.4550 mL | 30.9100 mL | 77.2750 mL |
| 5 mM | 0.6182 mL | 3.0910 mL | 6.1820 mL | 15.4550 mL | |
| 10 mM | 0.3091 mL | 1.5455 mL | 3.0910 mL | 7.7275 mL | |
| 15 mM | 0.2061 mL | 1.0303 mL | 2.0607 mL | 5.1517 mL | |
| 20 mM | 0.1545 mL | 0.7727 mL | 1.5455 mL | 3.8637 mL | |
| 25 mM | 0.1236 mL | 0.6182 mL | 1.2364 mL | 3.0910 mL | |
| 30 mM | 0.1030 mL | 0.5152 mL | 1.0303 mL | 2.5758 mL | |
| 40 mM | 0.0773 mL | 0.3864 mL | 0.7727 mL | 1.9319 mL | |
| 50 mM | 0.0618 mL | 0.3091 mL | 0.6182 mL | 1.5455 mL | |
| 60 mM | 0.0515 mL | 0.2576 mL | 0.5152 mL | 1.2879 mL |
Progesterone-d9 関連分類
HY-N0437S 関連分類
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