country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

製品番号: HY-184094

Copy Link Print Information

Risimtinib

(別名: Risimtinibum)

Risimtinib (Risimtinibum) is a FGFR1 inhibitor with an IC₅₀ of 2.1 nM. Risimtinib inhibits the proliferation of FGFR1-positive cancer cells. Risimtinib is used for the research of myeloid leukemia.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 2126751-11-7
分子式: C₃₀H₃₁N₅O₃
分子量:509.60

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Risimtinib 構造式

CAS 番号: 2126751-11-7

容量

価格（税別）

在庫状況

数量

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

IC₅₀ & Target^[1]

FGFR1

2.1 nM (IC₅₀)

体外実験

Risimtinib (compound 19a) potently inhibits purified FGFR1 kinase activity with an IC₅₀ of 2.1 nM^[1].
Risimtinib inhibits the proliferation of FGFR1-translocated KG-1 leukemia cells with an IC₅₀ of 14.9 nM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 2126751-11-7
分子量 509.60
分子式 C₃₀H₃₁N₅O₃
SMILES

CNC(C1=CC=CC2=C1C=CC(OC3=CC=NC(NC(C4=CC=C(N5C[C@H](N[C@H](C5)C)C)C=C4)=O)=C3)=C2)=O
別名

Risimtinibum
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Wei M, et al. Design, synthesis and biological evaluation of a series of novel 2-benzamide-4-(6-oxy-N-methyl-1-naphthamide)-pyridine derivatives as potent fibroblast growth factor receptor (FGFR) inhibitors. European journal of medicinal chemistry. 2018 Jun 25;154:9-28. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

お問い合わせ在庫あり

Other size

お問い合わせ