ROS 234
ROS 234 is a potent H3 antagonist, with a pKB of 9.46 for Guinea-pig ileum H3-receptor, a pKi of 8.90 for Rat cerebral cortex H3-receptor, and a ED50 of 19.12 mg/kg (ip) in ex vivo of Rat cerebral cortex. ROS 234 diaplays poor central access.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 184576-87-2
- 分子式: C13H15N5
- 分子量:241.29
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Histamine Receptor アイソフォーム固有の製品をすべて表示
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生物活性
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rat H3 receptor 8.90 (pKi) |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 184576-87-2
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分子量 241.29
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分子式 C13H15N5
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SMILES
C1(NCCCC2=CN=CN2)=NC3=CC=CC=C3N1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Ballabeni V, et al. CNS access of selected H3-antagonists: ex vivo binding study in rats. Inflamm Res. 2002 Apr;51 Suppl 1:S55-6. [Content Brief]
[2]. Mor M, et al. Synthesis, biological activity, QSAR and QSPR study of 2-aminobenzimidazole derivatives as potent H3-antagonists. Bioorg Med Chem. 2004 Feb 15;12(4):663-74. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
ROS 234 関連分類
HY-107563 関連分類
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