SR-3-65
SR-3-65 (compound 6) is a Indisulam (HY-13650) derivative,and inhibits the migration of gastric cancer cells. SR-3-65 attenuates PI3K/AKT/GSK-3β/β-catenin signaling pathway.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C16H9ClF3N3O2S
- 分子量:399.77
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
SR-3-65 (0.0001-100 µM, 48h) inhibits the cell growth of AGS cells with the IC50 of 24.75 μM[1].
SR-3-65 (10 µM, 48-72 h) shows anti-migration activity in AGS and MGC803 cells[1].
SR-3-65 (10 µM, 48 h) upregulates E-cadherin and downregulated N-cadherin and vimentin in AGS and MGC803 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:AGS cells
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Concentration:0.0001-100 µM
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Incubation Time:48 h
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Result:Inhibited the cell growth of AGS cells with the IC50 of 24.75 μM。
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Cell Line:AGS and MGC803 cells
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Concentration:10 µM
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Incubation Time:48-72 h
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Result:Showed anti-migration activity in AGS and MGC803 cells.
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Cell Line:MGC803 cells
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Concentration:10 µM
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Incubation Time:48 h
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Result:Upregulated E-cadherin and downregulated N-cadherin and vimentin.
化学情報
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分子量 399.77
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分子式 C16H9ClF3N3O2S
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SMILES
O=S(C1=CC=CC(C#N)=C1)(NC2=CC(C(F)(F)F)=CC3=C2NC=C3Cl)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
SR-3-65 関連分類
HY-161362 関連分類
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