Tauromustine
Tauromustine is an orally active nitrosourea anticancer agent. Tauromustine has an alkylation effect and can damage the DNA function. Tauromustine has a high therapeutic index, especially in the study of Walker 256 rat sarcoma. It is also active against melanoma, breast cancer, pleural mesothelioma and ovarian cancer. Tauromustine is mainly metabolized in the liver, but some of its metabolites also have cytotoxicity.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 85977-49-7
- 分子式: C7H15ClN4O4S
- 分子量:286.74
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
化学情報
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CAS 番号 85977-49-7
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分子量 286.74
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分子式 C7H15ClN4O4S
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SMILES
O=NN(CCCl)C(NCCS(=O)(N(C)C)=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Gregor A, et al. Phase II study of tauromustine in malignant glioma. Eur J Cancer. 1992;28A(12):1959-62. [Content Brief]
[2]. Smyth JF, et al. Two phase III trials of tauromustine (TCNU) in advanced colorectal cancer. Ann Oncol. 1995 Nov;6(9):948-9. [Content Brief]
[3]. Bibby MC, et al. Influence of hydralazine on the pharmacokinetics of tauromustine (TCNU) in mice. Br J Cancer. 1992 Mar;65(3):347-50. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Tauromustine 関連分類
HY-119916 関連分類
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