U 92032
U 92032 is a T-type Ca2+ channel antagonist. U 92032 inhibits Na+ channels. U-92032 inhibits thalamic oscillations. U 92032 can be used in the research of neurological diseases.
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- CAS 番号: 142223-92-5
- 分子式: C30H35F2N3O2
- 分子量:507.63
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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Calcium Channel アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
化学情報
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CAS 番号 142223-92-5
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分子量 507.63
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分子式 C30H35F2N3O2
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SMILES
O=C1C(=CC(=CC=C1CN2CCN(CC2)C(C3=CC=C(F)C=C3)C4=CC=C(F)C=C4)C(C)C)NCCO
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
プロトコル
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Ca2+ Staining Technique
Ca2+ staining is an experimental technique that utilizes specific fluorescent probes (such as Fluo-4 AM, Fura-2, etc.) to qualitatively or quantitatively detect dynamic changes in intracellular Ca2+ concentrations; this is achieved by monitoring the changes in fluorescent signals generated when these probes bind to free intracellular calcium ions. The underlying principle relies primarily on the presence of chelating groups within the probe's molecular structure that possess high affinity for calcium ions.
純度とドキュメンテーション
参考文献
[1]. Porcello DM, et al. Actions of U-92032, a T-type Ca2+ channel antagonist, support a functional linkage between I(T) and slow intrathalamic rhythms. J Neurophysiol. 2003 Jan;89(1):177-85. [Content Brief]
[2]. Avery RB, et al. Ca2+ channel antagonist U-92032 inhibits both T-type Ca2+ channels and Na+ channels in hippocampal CA1 pyramidal neurons. J Neurophysiol. 1997 Feb;77(2):1023-8. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
U 92032 関連分類
HY-105415 関連分類
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