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製品番号: HY-139175

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ZLY032

Name: ZLY032
Brand: MedChemExpress
SKU: HY-139175
Price: 125.00 USD
Availability: InStock
Rating: 5 (1 reviews)

ZLY032 is a dual FFA1/PPARδ agonist with the activity of improving glucose and lipid metabolism, alleviating liver fibrosis, and potentially inhibiting metabolic disorders.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 2314465-67-1
分子式: C₂₂H₁₈F₃NO₄S
分子量:449.44

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

ZLY032 構造式

CAS 番号: 2314465-67-1

容量

価格（税別）

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数量

Amount: USD 0.00

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

ZLY032 is a dual FFA1/PPARδ agonist with the activity of improving glucose and lipid metabolism, alleviating liver fibrosis, and potentially inhibiting metabolic disorders.

PPAR アイソフォーム固有の製品をすべて表示 :

Cellular Effect

Cell Line	Type	Value	Description	References
CHO	EC₅₀	68 nM Compound: 32	Agonist activity at human FFA1 receptor expressed in CHO cells by Fluo 4-AM dye based FLIPR assay Agonist activity at human FFA1 receptor expressed in CHO cells by Fluo 4-AM dye based FLIPR assay	[PMID: 30605833]
HEK293	EC₅₀	>10 μM Compound: 32	Transactivation of GAL4-fused human PPARalpha LBD expressed in HEK293 cells after 18 hrs by luciferase reporter gene assay Transactivation of GAL4-fused human PPARalpha LBD expressed in HEK293 cells after 18 hrs by luciferase reporter gene assay	[PMID: 30605833]
HEK293	EC₅₀	>10 μM Compound: 32	Transactivation of GAL4-fused human PPARgamma LBD expressed in HEK293 cells after 18 hrs by luciferase reporter gene assay Transactivation of GAL4-fused human PPARgamma LBD expressed in HEK293 cells after 18 hrs by luciferase reporter gene assay	[PMID: 30605833]
HEK293	EC₅₀	102 nM Compound: 32	Transactivation of GAL4-fused human PPARdelta LBD expressed in HEK293 cells after 18 hrs by luciferase reporter gene assay Transactivation of GAL4-fused human PPARdelta LBD expressed in HEK293 cells after 18 hrs by luciferase reporter gene assay	[PMID: 30605833]

化学情報

CAS 番号 2314465-67-1
分子量 449.44
分子式 C₂₂H₁₈F₃NO₄S
SMILES

OC(C[C@H]1C2=CC=C(OCC3=C(C)N=C(C4=CC=C(C=C4)C(F)(F)F)S3)C=C2OC1)=O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (265 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. ZLY032, the first-in-class dual FFA1/PPARδ agonist, improves glucolipid metabolism and alleviates hepatic fibrosis

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

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分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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