BET-IN-2
BET-IN-2 is a BET inhibitor with an IC50 of 52 nM for BRD4-BD1.
For research use only. We do not sell to patients.
- CAS No.: 2104688-91-5
- Formula: C23H29N3O
- Molecular Weight:363.50
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
BRD4 BD1 52 nM (IC50) |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MM1.S | IC50 |
0.016 μM
Compound: 54
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Antiproliferative activity against human MM1S cells after 72 hrs by CCK8 assay
Antiproliferative activity against human MM1S cells after 72 hrs by CCK8 assay
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[PMID: 28586718] |
Chemical Information
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CAS No. 2104688-91-5
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Molecular Weight 363.50
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Formula C23H29N3O
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SMILES
CC1=C([C@H](C)NC2=CC(N(C3CC3)[C@H](C)C(N4C)=O)=C4C=C2)C=CC(C)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BET-IN-2 Related Classifications
HY-102044 Related Classifications
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