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Cat. No.: HY-169184

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GDC-9918

GDC-9918 (compund GDC-9918) is a Janus kinase inhibitor.

For research use only. We do not sell to patients.

CAS No.: 2570375-06-1
Formula: C₂₀H₁₈F₂N₆O₅S
Molecular Weight:492.46

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

GDC-9918 Chemical Structure

CAS No.: 2570375-06-1

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

GDC-9918 (compund GDC-9918) is a Janus kinase inhibitor^[1].

IC₅₀ & Target

Janus^[1]

All JAK Isoforms :

Chemical Information

CAS No. 2570375-06-1
Molecular Weight 492.46
Formula C₂₀H₁₈F₂N₆O₅S
SMILES

O=C(C1=C2N=CC=CN2N=C1)NC3=CN(C)N=C3C4=CC(S(=O)(CCO)=O)=CC=C4OC(F)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Dalton D M, et al. Development of a Robust Pd-Catalyzed C–S Coupling for the Synthesis of Janus Kinase Inhibitor GDC-9918[J]. Organic Process Research & Development, 2024, 28(10): 3858-3870.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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GDC-9918

All JAK Isoforms