Phenothrin (Standard)
Phenothrin (Standard) is the analytical standard of Phenothrin (HY-B1072). This product is intended for research and analytical applications. Phenothrin is a voltage-gated sodium channel modulator. Phenothrin mainly acts on sodium channels in the closed resting state, slows their opening and closing, increases the steady-state sodium current, and prolongs the sodium current through slowly decaying tail currents. Phenothrin induces dose-dependent DNA damage and oxidative DNA damage in human peripheral blood lymphocytes and human hepatocytes. Phenothrin is used as an insecticide for agricultural, household, and public health insect control and for eliminating human lice infestations.
For research use only. We do not sell to patients.
- CAS No.: 26002-80-2
- Formula: C23H26O3
- Molecular Weight:350.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 26002-80-2
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Molecular Weight 350.45
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Formula C23H26O3
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SMILES
O=C(C1C(C)(C)C1/C=C(C)\C)OCC2=CC=CC(OC3=CC=CC=C3)=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Nagy K, et al. Evaluation of the genotoxicity of the pyrethroid insecticide phenothrin. Mutat Res Genet Toxicol Environ Mutagen. 2014;770:1-5. [Content Brief]
[2]. de Weille JR, et al. Interactions of pyrethroids and octylguanidine with sodium channels of squid giant axons. Brain research. 1988 Mar 29;445(1):1-11. [Content Brief]
[3]. Ruigt GS, et al. Increase of sodium current after pyrethroid insecticides in mouse neuroblastoma cells. Brain research. 1987 Dec 29;437(2):309-22. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Phenothrin (Standard) Related Classifications
HY-B1072R Related Classifications
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Keywords
- Phenothrin (Standard)
- 26002-80-2
- Reference Standards
- Environmental Pollutants
- Parasite
- Insecticide
- Sodium Channel
- DNA damage
- HepG2 hepatoblastoma cells
- genotoxin
- human hepatocytes
- human peripheral blood lymphocytes
- insecticide
- louse infestation
- oxidative DNA damage
- squid giant axons
- voltage-gated sodium channel
- Inhibitor
- inhibitor
- inhibit