SR2595
SR2595 is an inverse agonist of PPARγ with an IC50 of 30 nM.
For research use only. We do not sell to patients.
- CAS No.: 1415252-61-7
- Formula: C37H38N2O3
- Molecular Weight:558.71
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
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PPARγ 30 nM (IC50) |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK-293T | EC50 |
355 nM
Compound: 51
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Transactivation of human PPARgamma in HEK293T cells after 18 hrs by luciferase reporter gene assay
Transactivation of human PPARgamma in HEK293T cells after 18 hrs by luciferase reporter gene assay
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[PMID: 26396687] |
Chemical Information
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CAS No. 1415252-61-7
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Molecular Weight 558.71
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Formula C37H38N2O3
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SMILES
CC(N1CC2=CC=C(C=C2)C3=CC=CC=C3C(O)=O)=C(C4=C1C=CC(C(N[C@H](C5=CC=C(C=C5)C(C)(C)C)C)=O)=C4)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SR2595 Related Classifications
HY-116521 Related Classifications
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