2-Deethoxy-2-hydroxyphantomolin
2-Deethoxy-2-hydroxyphantomolin, Germacranolide, is an Antifungal and Antibacterial agent. 2-Deethoxy-2-hydroxyphantomolin can be isolated from Elephantopus tomentosus Linn and E. mollis. 2-Deethoxy-2-hydroxyphantomolin is moderately active against Candida albicans (14 mm clearing zone) and slightly active against Escherichia coli (12 mm), Pseudomonas aeruginosa (12 mm), Bacillus subtilis (14 mm), and Trichophyton mentagrophytes (13 mm).
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- CAS No.: 821799-76-2
- 화학식: C19H22O6
- 분자량:346.37
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
2-Deethoxy-2-hydroxyphantomolin (20.0 mg/mL; 24 h) inhibits Staphylococcus aureus with an inhibition zone diameter of 31.0 mm in an in vitro disk diffusion assay[1].
2-Deethoxy-2-hydroxyphantomolin is moderately active against Candida albicans (14 mm clearing zone, AI = 0.4) and slightly active against Escherichia coli (12 mm, AI = 0.2), Pseudomonas aeruginosa (12 mm, AI = 0.2), Bacillus subtilis (14 mm, AI = 0.4), and Trichophyton mentagrophytes (13 mm, AI = 0.3), with no activity against Staphylococcus aureus and Aspergillus niger[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 821799-76-2
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분자량 346.37
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화학식 C19H22O6
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SMILES
CC(C(O[C@@H]1[C@]2([H])[C@@](OC(C2=C)=O)([H])[C@@]3([H])O[C@](C=C3C)(/C=C(C1)/C)O)=O)=C
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)