Copy Link Print Information

FCCP

(Synonyms: Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone)
120 Cited Publications
고객리뷰

Based on 120 publication(s) in Google Scholar

FCCP is an uncoupler of oxidative phosphorylation (OXPHOS) in mitochondria. FCCP induces activation of PINK1 leading to Parkin Ser65 phosphorylation.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

  • Purity: 99.69%
  • CAS No.: 370-86-5
  • 화학식: C10H5F3N4O
  • 분자량:254.17
  • 보관:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 1 year , -20°C, 6 months
  • FCCP Chemical Structure
    FCCP Chemical Structure
  • Experimental Validation Results for FCCP
  • Experimental Validation Results for FCCP
  • Experimental Validation Results for FCCP
  • Experimental Validation Results for FCCP
  • Experimental Validation Results for FCCP
  • Experimental Validation Results for FCCP
CAS No.: 370-86-5
사이즈
가격
재고
수량
Amount: USD 0.00
Please select quantity
or
or

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
Other Forms of FCCP:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
주변의 대리점 찾기 Your local distributor: Hycultec GmbHHycultec
  • Biological Activity
  • Chemical Information
  • 용액&용해도
  • Protocol
  • 순도&문서
  • References
  • Help & FAQs
You May Still Need
Top Publications Citing

Use of MCE Products

Publications Citing Use of MedChemExpress (MCE) FCCP

More
Customer Validation & Images
Bio/Physico-chemical AssayCell Imaging/StainingFlow CytometryIFWBCell Proliferation/Viability Assay
  • Bio/Physico-chemical Assay
  • Cell Imaging/Staining
  • IF
  • WB
  • Cell Proliferation/Viability Assay
  • Flow Cytometry
Keywords
100 mg

견적 받기 해외재고보유

Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress 로그인
Register
Sign in to MedChemExpress
회원가입

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • FCCP Chemical Structure
    FCCP Chemical Structure
    1/16
  • 1/16

    FCCP purchased from MedChemExpress. Usage Cited in: Nature. 2025 Mar;639(8055):765-775. [Abstract]

    Customer Validation
     OCR of neuroendocrine (n=4) and non-neuroendocrine (n=2) SCLC cell lines after FCCP (1.5 μM, 40 min) treatment (n=6 technical replicates for each cell line).

  • 1/16

    FCCP purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Jul 30;16(1):6996. [Abstract]

    Customer Validation
     The mitophagy index of shRNA- or non-transduced 528NS and HOG-GSCs treated for 3 days with or without MitoTEMPOL (100 nM) on day 4 after shRNA transduction. FCCP (30 μM) and RA were used as positive controls.

  • 1/16

    FCCP purchased from MedChemExpress. Usage Cited in: Bone Res. 2024 Aug 28;12(1):49. [Abstract]

    Customer Validation
     Immunofluorescence staining to show the CTSK expression level in osteoclasts that were treated with oligomycin A (10 nmol/L), rotenone (100 nmol/L), FCCP (1 μmol/L), 2DG (1 μmol/L) or 3BrPA (1 μmol/L) for 6 h (scale bar, 100 µm).

  • 1/16

    FCCP purchased from MedChemExpress. Usage Cited in: Bone Res. 2024 Aug 28;12(1):49. [Abstract]

    Customer Validation
     Immunoblots of the pre-proenzyme and active CTSK levels in osteoclasts treated with 2DG (1 μmol/L), FCCP (1 μmol/L), rotenone (100 nmol/L) or 3-BrPA (1 μmol/L) for 10 h. The MMP-9 and CTSB expression levels were also detected. DMSO-treated osteoclasts were used as controls.

  • 1/16

    FCCP purchased from MedChemExpress. Usage Cited in: Cancer Res. 2023 Dec 15;83(24):4063-4079. [Abstract]

    Customer Validation
     Viability of Glut5-overexpressing and control cells cultured for 24 hours under different conditions in the presence of Rotenone or FCCP (10 μmol/L).

  • 1/16

    FCCP purchased from MedChemExpress. Usage Cited in: Nat Commun. 2022 May 13;13(1):2673. [Abstract]

    Customer Validation
     Flow cytometry analysis of WT and Myo19 KO cells stained with 100 nM TMRM for 20 min. 5 μM FCCP treatment for 10 min was used as positive.

  • FCCP