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Cat. No.: HY-183918

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Amfenac ethyl ester

Amfenac ethyl ester is an orally active cyclooxygenase (COX) inhibitor. Amfenac ethyl ester exhibits antiinflammatory activity in rodent models. Amfenac ethyl ester can be used for the research of inflammation.

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CAS No.: 61941-57-9
화학식: C₁₇H₁₇NO₃
분자량:283.32

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Amfenac ethyl ester Chemical Structure

CAS No.: 61941-57-9

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
- In Vivo
Chemical Information
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Bioz

Biological Activity

제품 설명

All COX Isoforms :

In Vitro

Amfenac ethyl ester (compound 3) weakly inhibits cyclooxygenase with an IC₅₀ of 50 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Amfenac ethyl ester (compound 3) (4-100 mg/kg; p.o.; single dose) exhibits acute antiinflammatory activity in the Evans blue-carrageenan rat model^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Evans blue-Carrageenan-induced pleural
effusion rat model^[1]
Dosage:

4; 100 mg/kg
Administration:

p.o.; single dose
Result:

Produced a 24% decrease in average pleural fluid volume relative to control rats.

Chemical Information

CAS No. 61941-57-9
분자량 283.32
화학식 C₁₇H₁₇NO₃
SMILES

O=C(CC1=C(N)C(C(C2=CC=CC=C2)=O)=CC=C1)OCC
Initial Source

Freshwater turtles
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Walsh DA, et al. Antiinflammatory agents. 4. Syntheses and biological evaluation of potential prodrugs of 2-amino-3-benzoylbenzeneacetic acid and 2-amino-3-(4-chlorobenzoyl)benzeneacetic acid. J Med Chem. 1990;33(8):2296-2304. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- 제품 설명
- In Vitro
- In Vivo
Chemical Information
순도&문서
References

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Amfenac ethyl ester

All COX Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Amfenac ethyl ester Related Classifications

HY-183918 Related Classifications