Apoptosis inducer 42
Apoptosis inducer 42 is an apoptosis inducer. Apoptosis inducer 42 activates late apoptosis and inhibits IL-6 secretion. Apoptosis inducer 42 shows high cytotoxicity towards cancer cells. Apoptosis inducer 42 can be used for cancer research, such as colon cancer.
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- CAS No.: 66685-93-6
- 화학식: C11H13OPS
- 분자량:224.26
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
IC50 & Target
[1]|
IL-6 |
In Vitro
Apoptosis inducer 42 (Compound 11) inhibits SW480, SW620, PC3f, HCT116 and HaCaT cells growth with IC50 values of 5.1, 6.3,6.0, 4.4 and 14.2 μM, respectively[1].
Apoptosis inducer 42 (4.4-6.3 μM, 72 h) reduces the amount of live cells in SW480, SW620, PC3f and HCT116 cells[1].
Apoptosis inducer 42 (4.4-6.3 μM, 72 h) activates late apoptosis and inhibits IL-6 secretion in SW480, SW620, PC3f and HCT116 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:SW480, SW620, PC3f and HCT116 cells
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Concentration:5.1 μM in SW480, 6.3 μM in SW620, 6.0 μM in PC3f, 4.4 μM in HCT116 cells
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Incubation Time:72 h
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Result:Activated >80% late apoptosis.
Chemical Information
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CAS No. 66685-93-6
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분자량 224.26
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화학식 C11H13OPS
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SMILES
O=C1CCP(C2=CC=CC=C2)(CC1)=S
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Apoptosis inducer 42 Related Classifications
HY-175609 Related Classifications
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