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Cat. No.: HY-N17356

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Atalaphyllidine

Atalaphyllidine is a natural product. Atalaphyllidine can be isolated from the stem bark of Glycosmis chlorosperma. Atalaphyllidine inhibits DYRK1A kinase activity with an IC₅₀ of 2.2 μM. Atalaphyllidine can be used in the research of neurodegenerative diseases.

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CAS No.: 57959-88-3
화학식: C₁₈H₁₅NO₄
분자량:309.32

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Atalaphyllidine Chemical Structure

CAS No.: 57959-88-3

사이즈

가격

재고

수량

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- Cellular Effect
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target^[1]

DYRK1A

2.2 μM (IC₅₀)

All DYRK Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	6.98 μM Compound: 9	Antiproliferative activity against human A549 cells after 3 days by alamar blue assay Antiproliferative activity against human A549 cells after 3 days by alamar blue assay	[PMID: 10217715]

In Vitro

Atalaphyllidine (30 min) inhibits DYRK1A kinase activity with an IC₅₀ of 2.2 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 57959-88-3
분자량 309.32
화학식 C₁₈H₁₅NO₄
SMILES

O=C1C2=C(NC3=C4C=CC(C)(C)OC4=CC(O)=C13)C(O)=CC=C2
Structure Classification
- Alkaloids
- Other Alkaloids
Initial Source
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Beniddir MA, et al. Acridone alkaloids from Glycosmis chlorosperma as DYRK1A inhibitors. J Nat Prod. 2014;77(5):1117-1122. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
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상품명:
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Atalaphyllidine

All DYRK Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Atalaphyllidine Related Classifications

HY-N17356 Related Classifications